Kleijnen Systematic Reviews Ltd has been commissioned to prepare a range of systematic reviews for governmental and other publicly funded bodies, health insurance associations, pharmaceutical companies and organisations that deliver health services. We aim to make the protocols and resulting reports publicly available whenever feasible.
Please visit these pages regularly for new information.
Systematic review and meta-analysis of the clinical safety and tolerability of ibuprofen compared with paracetamol in paediatric pain and fever.
Commissioned by Reckitt Benckiser, UK. End date August 2008.
Current Medical Res Opinion 2009 Jul 17. [Epub ahead of print]
PMID: 19606950
The effectiveness and safety of proton radiation therapy.
Commissioned by University Hospital Bern, Switzerland. End date June 2007
http://www.springerlink.com/content/tu7p2231r665/?p=69fe94cc22024fa7a1f4554e099faf4b&pi=0
Procedures and methods for benefit assessments in Germany.
Commissioned by VFA (German Association of Research-Based Pharmaceutical Companies), Germany. End date April 2008.
English version: http://www.springerlink.com/content/217585635q3j3921
German version: http://www.thieme-connect.de/ejournals/toc/dmw/68327
The application of quantitative methods for identifying and exploring bias in systematic reviews: PDE-5 inhibitors for erectile dysfunction.
Original project commissioned by Pfizer; work related to journal publication by KSR Ltd.
International Journal of Impot Res 2007; Dec 6 [Epub ahead of print]
Systematic review of test accuracy of screening with ultrasound in pregnancy.
[Ultraschall-Screening in der Schwangerschaft: Testgüte hinsichtlich der Entdeckungsrate fetaler Anomalien].
Commissioned by IQWiG, Germany. End date: June 2007.
http://www.iqwig.de/download/S05-03_Abschlussbericht_Ultraschallscreening_in_der_Schwangerschaft.pdf
Diagnostic accuracy and outcomes of ultrasound in the first trimester of pregnancy for detection of complications relevant for Austrian population, exclusive of screening for Down Syndrome.
Commissioned by Evidence Based Health Care in Hauptverband der Österreichischen Sozialversicherungsträger, Vienna, Austria. End date: April 2007.
http://www.hauptverband.at/mediaDB/131571.pdf
Vision screening in children under 6 years old. Systematic review of accuracy, effectiveness and effects of interventions after screening.
[Wissenschaftliche Bewertung des aktuellen medizinischen Wissenstands zur Früherkennungsuntersuchung von Sehstörungen von Kindern bis zur Vollendung des 6. Lebensjahres].
Commissioned by IQWiG, Germany. End date: April 2007.
http://www.iqwig.de/download/S05-02_Abschlussbericht_Sehscreening_bei_Kindern.pdf
Systematic review of (cost-)effectiveness of lifestyle interventions for people with impaired glucose tolerance or type 2 diabetes mellitus in combination with obesity.
Commissioned by College voor Zorgverzekeringen, Diemen, Netherlands. Completed: December 2006.
http://www.cvz.nl/resources/rpt-Kleijnen%20lifestyle-interventions_tcm28-22554.pdf
Systematic review of the (cost-)effectiveness of Spinal Cord Stimulation for people with chronic pain.
Commissioned by College voor Zorgverzekeringen, Diemen, Netherlands. Completed: December 2006.
Clinical Journal of Pain 2008; 24:741-756
http://www.cvz.nl/resources/rpt-Kleijnen%20SCS-spinalcordstimulation_tcm28-22555.pdf
Hearing screening in newborns. Systematic review of accuracy, effectiveness and effects of interventions after screening.
[Wissenschaftliche Bewertung des aktuellen medizinischen Wissenstands zu
frueherkennungsuntersuchung von Hoerstoerungen bei Neugeborenen].
Commissioned by IQWiG, Germany. Completed: September 2006.
http://www.iqwig.de/download/S05-01_Abschlussbericht_Frueherkennungsuntersuchung_von_Hoerstoerungen_bei_Neugeborenen.pdf
Guidelines, effectiveness and cost-effectiveness of key interventions to allergic conditions. A Review of Reviews.
Commissioned by the Department of Health, U.K. Completed: June 2006.
http://www.dh.gov.uk/assetRoot/04/13/73/79/04137379.pdf